Consult your healthcare provider for personalized advice based on the medications you take. Consult your healthcare provider for medical advice. If you are already taking Prevacid or Prilosec, and find out you are pregnant, consult your doctor. Prevacid, or lansoprazole, is a proton pump inhibitor. It works by decreasing acid production and helping symptoms of acid reflux. Prevacid is available by prescription as well as OTC over-the-counter in both brand-name and generic.
Prilosec, or omeprazole, is also a drug in the proton pump inhibitor class of medications. It is available in both prescription and OTC form, in both brand and generic.
Because they are in the same drug class, they work in the same way but have some differences in indications, cost, drug interactions, side effects, and warnings. Looking at the available data, both PPIs seem to be similar in terms of safety and efficacy.
Prevacid may be slightly more effective in the short-term, but over time, the drugs have similar results. Your doctor can help you decide if Prevacid or Prilosec is right for you. It is difficult to say. There is some conflicting information and not enough information. Although the manufacturers of each drug do not specifically warn against alcohol in combination with the medication, drinking alcohol can increase acidity and worsen the symptoms of reflux.
Both Prilosec and Prevacid come with warnings, which are detailed above. Your doctor will monitor your response, as well as any adverse reactions, to Prevacid or Prilosec. Comparing lansoprazole and omeprazole in onset of heartburn relief: results of a randomized, controlled trial in erosive esophagitis patients. Am J Gastroenterol ; Theoretically, differences in pharmacokinetic properties, such as increased bioavailability of lansoprazole, could play a role in efficacy of symptom control.
To enter the study, patients had to have experienced at least 1 episode of moderate to very severe heartburn within 3 days before their screening visit. Allocation concealment was not mentioned. Follow-up visits were conducted at the end of weeks 1, 2, and 8 of treatment. Astra-Zeneca, the manufacturer. Bob : I knew you would jump on the inappropriate comparison of esomeprazole with omeprazole.
Another problem with this comparison is that a true clinical end point is not being measured. But I have the same complaints as I did with the GERD studies regarding the use of unequal dosages and using endoscopic cure rates as the end point. And do I even have to do the H. Sixteen studies with no differences noted among any PPIs. Bob : Meta-analysis can be tricky. A series of principles needs to be followed for the results to be valid. In this study, the authors appropriately identified a clear study question, performed a fairly comprehensive review of available databases although they did not include any abstracts from presentations at symposia or obtain unpublished clinical trials from the FDA or the drug companies , and used clear end points to determine cure or failure—so far, so good.
The most obvious faux pas the authors made was not grading the quality of the studies they incorporated in this meta-analysis. They did, however, redeem them-selves slightly by incorporating only randomized prospective trials.
Mark : This faux pas is a problem. How do we know that the studies they included were any good? We don't. I like their conclusions and I am sure they are correct, but they need to grade the papers included in their analysis; other-wise, we have no assurance that they were any good.
Bob : I feel comfortable saying there are no differences in efficacy among any PPIs for the above conditions. It also has been suggested that PPIs are associated with increased rates of community-acquired pneumonia 1 and Clostridium difficile colitis.
Andrea : There are no differences among PPIs except cost, so go with the cheapest. However, the cheapest is not what ends up in our sample cabinet. Mark : I agree—save your patient some cash and go for the less expensive drug.
Main Points. Make sure that any article that evaluates treatments uses equipotent dosages of the drugs being compared. Indication As proton pump inhibitors, both Prevacid and Prilosec are good at treating gastroesophageal reflux disease GERD , a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus.
The following video further explains how proton pump inhibitors work. Form Prevacid comes as 15 and 30mg capsules as well as 15 and 30mg orally-disintegrating tablets. Directions for Use Both drugs should be taken orally or as directed by a doctor , usually once daily before a meal.
Storage and Shelf Life Both Prevacid and Prilosec should be stored at room temperature, away from light, excessive heat , and moisture.
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